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PSB-12062
PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).
Catalog No. T12568Cas No. 55476-47-6
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Purity:99.97%
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PSB-12062
Catalog No. T12568Alias N-(p-Methylphenylsulfonyl)phenoxazineCas No. 55476-47-6
PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $43 | In Stock | |
| 25 mg | $77 | In Stock | |
| 50 mg | $137 | In Stock | |
| 100 mg | $208 | In Stock | |
| 200 mg | $297 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4). |
| Targets&IC50 | P2X4 (mouse):1.76 μM , P2X4 (human):1.38 μM , P2X4 (rat):92.8 nM |
| In vitro | PSB-12062 is a selective P2X4 antagonist that was equally potent in all three species (IC(50): 0.928-1.76 μM). The compounds showed an allosteric mechanism of action. |
| Alias | N-(p-Methylphenylsulfonyl)phenoxazine |
| Molecular Weight | 337.39 |
| Formula | C19H15NO3S |
| Cas No. | 55476-47-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.37 mg/mL (10 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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