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PSB-12062

Catalog No. T12568Cas No. 55476-47-6
Alias N-(p-Methylphenylsulfonyl)phenoxazine

PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).

PSB-12062

PSB-12062

Purity: 99.97%
Catalog No. T12568Alias N-(p-Methylphenylsulfonyl)phenoxazineCas No. 55476-47-6
PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$43In Stock
25 mg$77In Stock
50 mg$137In Stock
100 mg$208In Stock
200 mg$297In Stock
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Purity:99.97%
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Product Introduction

Bioactivity
Description
PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).
Targets&IC50
P2X4 (rat):92.8 nM , P2X4 (human):1.38 μM , P2X4 (mouse):1.76 μM
In vitro
PSB-12062 is a selective P2X4 antagonist that was equally potent in all three species (IC(50): 0.928-1.76 μM). The compounds showed an allosteric mechanism of action.
AliasN-(p-Methylphenylsulfonyl)phenoxazine
Chemical Properties
Molecular Weight337.39
FormulaC19H15NO3S
Cas No.55476-47-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3.37 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9639 mL14.8196 mL29.6393 mL148.1964 mL
5 mM0.5928 mL2.9639 mL5.9279 mL29.6393 mL
10 mM0.2964 mL1.4820 mL2.9639 mL14.8196 mL

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