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PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | In Stock | |
10 mg | $43 | In Stock | |
25 mg | $77 | In Stock | |
50 mg | $137 | In Stock | |
100 mg | $208 | In Stock | |
200 mg | $297 | In Stock |
Description | PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4). |
Targets&IC50 | P2X4 (rat):92.8 nM , P2X4 (human):1.38 μM , P2X4 (mouse):1.76 μM |
In vitro | PSB-12062 is a selective P2X4 antagonist that was equally potent in all three species (IC(50): 0.928-1.76 μM). The compounds showed an allosteric mechanism of action. |
Alias | N-(p-Methylphenylsulfonyl)phenoxazine |
Molecular Weight | 337.39 |
Formula | C19H15NO3S |
Cas No. | 55476-47-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 3.37 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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