Shopping Cart
- Remove All
Your shopping cart is currently empty
Pasireotide Acetate
Catalog No. TP2207Cas No. 396091-76-2
Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively.
Pasireotide Acetate
Catalog No. TP2207Cas No. 396091-76-2
Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $97 | In Stock | |
| 5 mg | $449 | In Stock | |
| 10 mg | $659 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,390 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Pasireotide Acetate"
2-Aminoethanethiol
β-Mercaptoethylamine, β-MEA, Cysteamine, 2-Mercaptoethylamine
T108060-23-1
2-Aminoethanethiol (Cysteamine) is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
- $45
Size
QTY
L-797,591 hydrochloride
L-797,591 hydrochloride(217480-24-5 Free base)
T27787LIn house
L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride significantly enhanced p38 phosphorylation in cotransfected cells, and this effect was reversed in combination with AG1478.
- $400
Size
QTY
Somatostatin acetate
Somatostatin acetate（51110-01-1 Free base）
TP1302L
Somatostatin acetate is an endogenously secreted inhibitor of cell proliferation with potential antitumor activity for the study of cancer and neurological disorders.
- $54
Size
QTY
FK962
T7829283167-06-6
FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.
- $31
Size
QTY
BIM-23190 aceate
T39262L
BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.
- $195
Size
QTY
Cortistatin 14, human, rat acetate
TP1188L
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and remarkable anti-inflammatory properties. Cortistatin 14, human, rat acetate binds and exerts its fun
- $111
Size
QTY
CYN 154806 TFA
CYN 154806 TFA
TP13462828432-46-6
CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48, respectively.
- $147
Size
QTY
L-796,778
L 796,778
T32511217480-25-6
L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.
- $195
Size
QTY
(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid
T776702919211-45-1
(1R,5S,6r)-N-(2-methyl-1-((3-methylpyridin-2-yl)oxy)propan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide L(+)-Tartaric acid is a potential SSTR4 agonist.
- $195
Size
QTY
L-803087
T11800217480-26-7
L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, demonstrating over 280-fold selectivity compared to other growth inhibitory receptors. L-803087 induces AMPA-mediated synaptic responses in the hippocampus in vitro and increases seizures in alginate-induced seizure-busting mice in vivo.
- $117
Size
QTY
Cyclosomatostatin Acetate
Cyclosomatostatin Acetate （84211-54-1 Free base）
T21567L
Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer cells.
- $153
Size
QTY
Octreotide Acetate
SMS 201-995 (acetate), SMS 201995, Sandostatin, Longastatin
T411979517-01-4
Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone.
- $30
Size
QTY
Select Batch
Purity:99.92%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively. |
| In vitro | Pasireotide (SOM230) acetate enhances agonist activity at growth inhibitory receptors with pKi of 8.2, 9.0, 9.1, less than 7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively. |
| In vivo | METHODS: Pasireotide (SOM230) acetate (160 mg/kg, subcutaneous injection, four months) was administered to a MEN1 transgenic mouse model, and the effects of Pasireotide (SOM230) acetate on insulin secretion, glucose levels, tumor growth and survival were tested. RESULTS Pasireotide (SOM230) acetate significantly decreased serum insulin, increased serum glucose, decreased tumor size and increased Pdx1-Cre cell apoptosis. [1] |
| Molecular Weight | 1107.26 |
| Formula | C60H70N10O11 |
| Cas No. | 396091-76-2 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (45.16 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Pasireotide Acetate | purchase Pasireotide Acetate | Pasireotide Acetate cost | order Pasireotide Acetate | Pasireotide Acetate chemical structure | Pasireotide Acetate in vivo | Pasireotide Acetate in vitro | Pasireotide Acetate formula | Pasireotide Acetate molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.