Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 47.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 243.00 | |
50 mg | In stock | $ 423.00 | |
100 mg | In stock | $ 629.00 | |
500 mg | In stock | $ 1,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR. |
In vitro | Peretinoin (10-40 μM; 12-72 hours) exhibits suppressed SPHK1 expression after 24 h treatment, even at 10 μM and more prominent after 72 h peretinoin treatment [1]. Peretinoin (5 μM; 24 hours) up-regulates the expression of LC3B-II and increases autophagy flux in mouse primary hepatocytes [2]. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with an EC50 of 9 μM [3]. |
Cell Research | Cell Line: Mouse primary hepatocytes (MPH) and the human HCC HepG2 cell line. Concentration: 5 μM. Incubation Time: 24 hours [2] |
Synonyms | NIK333 |
Molecular Weight | 302.45 |
Formula | C20H30O2 |
CAS No. | 81485-25-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (165.32 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Peretinoin 81485-25-8 Autophagy GPCR/G Protein Metabolism Microbiology/Virology Proteases/Proteasome Retinoid Receptor HCV Protease S1P Receptor inhibit Retinoic acid receptors SphK Retinoid X receptors HCV Inhibitor NIK 333 Sphingosine kinase NIK-333 Hepatitis C virus RAR/RXR NIK333 inhibitor