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Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $96 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $372 | In Stock | |
25 mg | $629 | In Stock | |
50 mg | $896 | In Stock | |
100 mg | $1,220 | In Stock | |
1 mL x 10 mM (in DMSO) | $262 | In Stock |
Description | Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway. |
In vivo | ERK-IN-1 (50, 75 mg/kg, p.o., qd/q2d, 27 days) treatment significantly reduces the tumor volume in the Calu-6 human NSCLC subcutaneous tumor xenograft model in mice. |
Alias | ERK-IN-1 |
Molecular Weight | 578.42 |
Formula | C26H27BrF3N5O2 |
Cas No. | 1715025-32-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/ml (103.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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