Metabolism ROR SR0987


Catalog No. T4670   CAS 303126-97-8
Purity 99.43% Datasheet

SR0987 is a RORγt agonist,

SR0987, CAS 303126-97-8
Pack Size Availability Price/USD Quantity
5 mg In stock 77.00
10 mg In stock 131.00
25 mg In stock 266.00
50 mg In stock 446.00
100 mg In stock 797.00
1 mL * 10 mM (in DMSO) In stock 84.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description SR0987 is a RORγt agonist,
Targets&IC50 RORγt :ic50 800 nM (EC50),  
In vitro SR0987 treatment results in a statistically significant reduction of the surface expression of PD-1 whereas desmostrol treatment shows no effect. Treatment with SR0987 and or desmosterol results in a trend towards increased IL17 production.SR0987 clearly shows a concentration dependent induction of reporter gene expression with an EC50 of ~800nM.
Molecular Weight 397.7
Formula C16H10ClF6NO2
CAS No. 303126-97-8


-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )


References and Literature
2. Chang MR, et al. Synthetic RORγt Agonists Enhance Protective Immunity. ACS Chem Biol. 2016 Apr 15;11(4):1012-8.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Anti-cancer Compound Library

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