Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 29.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells. |
Source |
Synonyms | 1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol |
Molecular Weight | 138.12 |
Formula | C7H6O3 |
CAS No. | 533-31-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform, Dichloromethane, Ethyl Acetate: Soluble
DMSO: 25 mg/mL(181 mM)
You can also refer to dose conversion for different animals. More
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Sesamol 533-31-3 Apoptosis Chromatin/Epigenetic PI3K/Akt/mTOR signaling AMPK 1,3-Benzodioxol-5-ol 3,4-Methylenedioxyphenol Inhibitor inhibit inhibitor