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Synephrine

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Purity:100%

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COA HNMR HPLC LCMS

Synephrine

Catalog No. T1287Cas No. 94-07-5

Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.

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Pack Size	Price	Availability
10 mg	$40	In Stock
25 mg	$63	In Stock
50 mg	$81	In Stock
100 mg	$113	In Stock
500 mg	$273	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
In vitro	Synephrine is a compound commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. [1] [2] Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells. [3]
In vivo	LD50: Mice >1000 mg/kg (s.c.) [4]
Alias	Oxedrine

Chemical Properties

Molecular Weight	167.21
Formula	C9H13NO2
Cas No.	94-07-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 2 mg/mL (11.96 mM)

DMSO: 85 mg/mL (508.34 mM)

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	5.9805 mL	29.9025 mL	59.8050 mL	299.0252 mL
5 mM	1.1961 mL	5.9805 mL	11.9610 mL	59.8050 mL
10 mM	0.5981 mL	2.9903 mL	5.9805 mL	29.9025 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.2990 mL	1.4951 mL	2.9903 mL	14.9513 mL
50 mM	0.1196 mL	0.5981 mL	1.1961 mL	5.9805 mL
100 mM	0.0598 mL	0.2990 mL	0.5981 mL	2.9903 mL

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In Vivo Formulation Calculator (Clear solution)

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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