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A2764 dihydrochloride

🥰Excellent
Catalog No. T7775Cas No. 861038-72-4

A2764 dihydrochloride is a highly selective inhibitor of TWIK-related spinal cord K+ channel (TRESK).

A2764 dihydrochloride

A2764 dihydrochloride

🥰Excellent
Purity: 99.05%
Catalog No. T7775Cas No. 861038-72-4
A2764 dihydrochloride is a highly selective inhibitor of TWIK-related spinal cord K+ channel (TRESK).
Pack SizePriceAvailabilityQuantity
5 mg$35In Stock
10 mg$58In Stock
25 mg$103In Stock
50 mg$173In Stock
100 mg$269In Stock
200 mg$385In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.05%
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Product Introduction

Bioactivity
Description
A2764 dihydrochloride is a highly selective inhibitor of TWIK-related spinal cord K+ channel (TRESK).
Targets&IC50
TRESK activated channel (mouse):(6.8 μM)
Chemical Properties
Molecular Weight351.7
FormulaC15H21Cl3N2O
Cas No.861038-72-4
SmilesCl.Cl.CCN(CC)CCOc1ccc(Cl)c2cccnc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 41.67 mg/mL (118.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8433 mL14.2167 mL28.4333 mL142.1666 mL
5 mM0.5687 mL2.8433 mL5.6867 mL28.4333 mL
10 mM0.2843 mL1.4217 mL2.8433 mL14.2167 mL
20 mM0.1422 mL0.7108 mL1.4217 mL7.1083 mL
50 mM0.0569 mL0.2843 mL0.5687 mL2.8433 mL
100 mM0.0284 mL0.1422 mL0.2843 mL1.4217 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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