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AGPS-IN-2i
🥰Excellent
Catalog No. T69685Cas No. 2316782-88-2
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation.
AGPS-IN-2i
🥰Excellent
Catalog No. T69685Cas No. 2316782-88-2
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $109 | In Stock | |
| 5 mg | $263 | In Stock | |
| 10 mg | $389 | In Stock | |
| 25 mg | $652 | In Stock | |
| 50 mg | $847 | In Stock |
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells. AGPS-IN-2i had an inhibitory effect on cancer cell proliferation. |
| In vitro | AGPS-IN-2i (2i) (500 µM ; 24 h) reduced ether lipids levels and cell migration rate In 231MFP cancer cells.[1] 2i (50、100 µM ; 24 h) specifically impaired epithelial to mesenchymal transition (EMT) by modulating E-cadherin, Snail, and MMP2 expression levels in PC-3 and MDA-MB-231 cancer cells.[1] |
| Molecular Weight | 345.34 |
| Formula | C18H17F2N3O2 |
| Cas No. | 2316782-88-2 |
| Smiles | C(NC(CC(C)C1=C(F)C=CC=C1F)=O)C=2C=C3C(=CC2)NC(=O)N3 |
Storage & Solubility Information
| Storage | store at low temperature | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (65.15 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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