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AZD4635

Catalog No. T4265Cas No. 1321514-06-0
Alias HTL1071

AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).

AZD4635

AZD4635

Purity: 99.61%
Catalog No. T4265Alias HTL1071Cas No. 1321514-06-0
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
2 mg$44In Stock
5 mg$72In Stock
10 mg$118In Stock
25 mg$198In Stock
50 mg$312In Stock
100 mg$480In Stock
500 mg$1,060In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Purity:99.61%
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Product Introduction

Bioactivity
Description
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
Targets&IC50
A2AR:Ki: 1.7 nM
AliasHTL1071
Chemical Properties
Molecular Weight315.73
FormulaC15H11ClFN5
Cas No.1321514-06-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83.3 mg/mL (263.83 mM)
H2O: < 0.1 mg/mL (insoluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1673 mL15.8363 mL31.6726 mL158.3632 mL
5 mM0.6335 mL3.1673 mL6.3345 mL31.6726 mL
10 mM0.3167 mL1.5836 mL3.1673 mL15.8363 mL
20 mM0.1584 mL0.7918 mL1.5836 mL7.9182 mL
50 mM0.0633 mL0.3167 mL0.6335 mL3.1673 mL
100 mM0.0317 mL0.1584 mL0.3167 mL1.5836 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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