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BML-284 hydrochloride

BML-284 hydrochloride
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Purity:99.79%
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BML-284 hydrochloride

Catalog No. T8820Cas No. 2095432-75-8
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
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Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$62In Stock
10 mg$81In Stock
25 mg$153In Stock
50 mg$281In Stock
100 mg$487In Stock
200 mg$683In Stock
500 mg$1,070In Stock
1 mL x 10 mM (in DMSO)$91In Stock
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Product Introduction

Bioactivity
Description
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
In vitro
BML-284 HCL does not inhibit the activity of GSK-3β, and may be a useful tool in the study of physiological processes that involve the Wnt pathway.
In vivo
In a Xenopus model, Wnt agonist 1 (10 μM) mimics the effects of Wnt at the whole-organism level, and affects Xenopus embryonic head specification.
AliasBML-284 HCL, Wnt agonist 1 HCL
Chemical Properties
Molecular Weight386.84
FormulaC19H19ClN4O3
Cas No.2095432-75-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 9 mg/mL (23.27 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5850 mL12.9252 mL25.8505 mL129.2524 mL
5 mM0.5170 mL2.5850 mL5.1701 mL25.8505 mL
10 mM0.2585 mL1.2925 mL2.5850 mL12.9252 mL
20 mM0.1293 mL0.6463 mL1.2925 mL6.4626 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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