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Chelidonic acid

Chelidonic acid
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Purity:98%
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Chelidonic acid

Catalog No. T5558Cas No. 99-32-1
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity.
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Pack SizePriceAvailabilityQuantity
50 mg$33In Stock
100 mg$48In Stock
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Product Introduction

Bioactivity
Description
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity.
In vivo
Chelidonic acid (0.2, 2 mg/kg p.o.) attenuates allergic reaction induced by ovalbumin in mice[3]. Chelidonic acid may attenuate allergic reactions by inhibiting caspase-1 activity.
Animal Research
female BALB/c mice was Maintained 6-week-old under pathogen-free conditions.?Sensitized mice on days 1, 5, and 14 by intraperitoneal ?injection of 100 μg OVA emulsified in 20 mg aluminum hydroxide and we challenged mice with 1.5 mg OVA.?Chelidonic acid was administrated orally before intranasal .?OVA challenge for 10 days.?Nasal symptoms were evaluated by counting the number of nasal rubs that occurred in the 10 min after OVA. provocation at 10 days after challenge.
AliasJervaic acid, Jerva acid, γ-Pyrone-2,6-dicarboxylic acid
Chemical Properties
Molecular Weight184.1
FormulaC7H4O6
Cas No.99-32-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 4 mg/mL (21.72 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.4318 mL27.1592 mL54.3183 mL271.5915 mL
5 mM1.0864 mL5.4318 mL10.8637 mL54.3183 mL
10 mM0.5432 mL2.7159 mL5.4318 mL27.1592 mL
20 mM0.2716 mL1.3580 mL2.7159 mL13.5796 mL

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