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Clinafloxacin

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Catalog No. T1283Cas No. 105956-97-6
Alias PD 127391, CI-960, AM-1091

Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.

Clinafloxacin

Clinafloxacin

🥰Excellent
Purity: 98.87%
Catalog No. T1283Alias PD 127391, CI-960, AM-1091Cas No. 105956-97-6
Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.
Pack SizePriceAvailabilityQuantity
2 mg$36 In Stock
5 mg$56 In Stock
10 mg$80 In Stock
25 mg$132 In Stock
50 mg$195 In Stock
100 mg$289 In Stock
200 mg$428 In Stock
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Purity:98.87%
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Product Introduction

Bioactivity
Description
Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.
Targets&IC50
parC-gyrA mutants (S. pneumonia):1 μg/ml (MIC)
In vivo
Clinafloxacin is an effective broad-spectrum antibiotic exhibiting potent in vitro activity against Gram-positive, Gram-negative, and anaerobic pathogens, and is particularly efficacious against Streptococcus pneumoniae. It demonstrates high activity in Streptococcus pneumoniae strain 7785 (MIC=0.125μg/ml).
AliasPD 127391, CI-960, AM-1091
Chemical Properties
Molecular Weight365.79
FormulaC17H17ClFN3O3
Cas No.105956-97-6
SmilesClC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(N)CC3)C4CC4
Relative Density.1.573 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1.83 mg/mL (5 mM), Sonication is recommended.
H2O: 1 mg/mL (2.73 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.7338 mL13.6690 mL27.3381 mL136.6905 mL
DMSO
1mg5mg10mg50mg
5 mM0.5468 mL2.7338 mL5.4676 mL27.3381 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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