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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $129 | In Stock | |
5 mg | $428 | In Stock | |
10 mg | $762 | In Stock | |
25 mg | $1,560 | In Stock | |
50 mg | $2,110 | In Stock | |
100 mg | $2,860 | In Stock |
Description | γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. |
Targets&IC50 | Notch:0.24 nM, β-amyloid(40):0.24 nM, β-amyloid(42):0.37 nM |
In vitro | At a concentration of 50 μM, compound E reduces the proliferation of T47D and MCF-7 cell lines by less than 50% [2]. |
Alias | Compound E |
Molecular Weight | 490.5 |
Formula | C27H24F2N4O3 |
Cas No. | 209986-17-4 |
Storage | keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (163.10 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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