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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $68 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $225 | In Stock | |
50 mg | $378 | In Stock | |
100 mg | $597 | In Stock | |
500 mg | $1,260 | In Stock | |
1 mL x 10 mM (in DMSO) | $75 | In Stock |
Description | CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2). |
In vitro | CPDA enhances insulin signaling. CPDA was found to enhance in vitro insulin signaling through the Akt pathway more efficiently than the previously reported SHIP2 inhibitor AS1949490, and ameliorated abnormal glucose metabolism in diabetic (db/db) mice. |
In vivo | CPDA significantly enhances abnormal glucose metabolism in diabetic animals, as evidenced by its effectiveness in improving glucose metabolism in db/db mice. |
Molecular Weight | 388.8 |
Formula | C20H15ClF2N2O2 |
Cas No. | 1415834-63-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (128.60 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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