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Cyclothiazide

Cyclothiazide
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Purity:98.74%
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Cyclothiazide

Catalog No. T4573Cas No. 2259-96-3
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its response to glutamic acid (EC50 = 3.8 M).
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Pack SizePriceAvailabilityQuantity
2 mg$34In Stock
5 mg$55In Stock
10 mg$89In Stock
25 mg$178In Stock
50 mg$287In Stock
100 mg$455In Stock
200 mg$657In Stock
500 mg$987In Stock
1 mL x 10 mM (in DMSO)$61In Stock
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Product Introduction

Bioactivity
Description
Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptorsthat potently inhibits AMPA receptor desensitization, positively modulating its response to glutamic acid (EC50 = 3.8 M).
Chemical Properties
Molecular Weight389.88
FormulaC14H16ClN3O4S2
Cas No.2259-96-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Ethanol: 25mM
DMSO: 15 mg/mL (38.47 mM)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.5649 mL12.8245 mL25.6489 mL128.2446 mL
5 mM0.5130 mL2.5649 mL5.1298 mL25.6489 mL
10 mM0.2565 mL1.2824 mL2.5649 mL12.8245 mL
20 mM0.1282 mL0.6412 mL1.2824 mL6.4122 mL
DMSO
1mg5mg10mg50mg
50 mM0.0513 mL0.2565 mL0.5130 mL2.5649 mL
100 mM0.0256 mL0.1282 mL0.2565 mL1.2824 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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