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D-Panthenol

Catalog No. T1437Cas No. 81-13-0
Alias Pantothenol, Ilopan, D-Pantothenyl alcohol, Dexpanthenol

D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is unclear, it may enhance the effect of acetylcholine. D-Panthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

D-Panthenol

D-Panthenol

Purity: 99.74%
Catalog No. T1437Alias Pantothenol, Ilopan, D-Pantothenyl alcohol, DexpanthenolCas No. 81-13-0
D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is unclear, it may enhance the effect of acetylcholine. D-Panthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.
Pack SizePriceAvailabilityQuantity
200 mg$31In Stock
500 mg$46In Stock
1 g$53In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.74%
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Product Introduction

Bioactivity
Description
D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is unclear, it may enhance the effect of acetylcholine. D-Panthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.
In vivo
Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2].
AliasPantothenol, Ilopan, D-Pantothenyl alcohol, Dexpanthenol
Chemical Properties
Molecular Weight205.25
FormulaC9H19NO4
Cas No.81-13-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (219.24 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8721 mL24.3605 mL48.7211 mL243.6054 mL
5 mM0.9744 mL4.8721 mL9.7442 mL48.7211 mL
10 mM0.4872 mL2.4361 mL4.8721 mL24.3605 mL
20 mM0.2436 mL1.2180 mL2.4361 mL12.1803 mL
50 mM0.0974 mL0.4872 mL0.9744 mL4.8721 mL
100 mM0.0487 mL0.2436 mL0.4872 mL2.4361 mL

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