Shopping Cart
- Remove All
Your shopping cart is currently empty
Ethynodiol diacetate
Catalog No. T0996Cas No. 297-76-7
Alias Ethynodiol acetate, 8080 CB
Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone utilized alone or combined with estrogens as an oral contraceptive.
Ethynodiol diacetate
Catalog No. T0996Alias Ethynodiol acetate, 8080 CBCas No. 297-76-7
Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone utilized alone or combined with estrogens as an oral contraceptive.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $35 | In Stock | |
| 1 g | $48 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Ethynodiol diacetate"
Kaempferol
Cited
Robigenin, Kempferol
T2177520-18-3
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
ApoptosisAutophagyEndogenous MetaboliteEstrogen Receptor/ERREstrogen/progestogen ReceptorHIV ProteaseMitophagyParasite
- $46
Size
QTY
CitedEthisterone
Pregneninolone, 17α-Ethynyltestosterone
T0301434-03-7
Ethisterone (17α-Ethynyltestosterone) is a progestogen hormone.
- $50
Size
QTY
Melatonin Cited
N-Acetyl-5-methoxytryptamine, Melatonine
T165973-31-4
Melatonin (Melatonine) is a natural hormone secreted by the pineal gland that activates melatonin receptors. Melatonin is a hormone that regulates the biological clock and also has antioxidant and anti-inflammatory activities.
ApoptosisAutophagyCaMKEndogenous MetaboliteEstrogen/progestogen ReceptorGlutathione PeroxidaseMelatonin ReceptorMitophagyROR
- $31
Size
QTY
CitedMifepristone
RU486, RU 38486, C-1073
T110284371-65-3
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
- $37
Size
QTY
Estradiol Cited
β-Estradiol, E2, 17β-Oestradiol, 17β-Estradiol
T104850-28-2
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor beta (ERβ).
- $30
Size
QTY
CitedAstragaloside IV
Cited
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
- $32
Size
QTY
CitedEstradiol benzoate Cited
Benzoestrofol, Benzhormovarine, Benovocylin
T038450-50-0
Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
- $45
Size
QTY
CitedAllura Red AC
FD&C RED NO. 40, CI 16035, Allura Red
TN137025956-17-6
Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal serotonin.
- $50
Size
QTY
Natamycin Cited
Pimaricin
T07097681-93-8
Natamycin (Pimaricin) is a Polyene Antimicrobial.
- $38
Size
QTY
CitedEstrone
Oestrone, Fluoroethyl, Aquacrine
T100953-16-7
Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
- $46
Size
QTY
Progesterone Cited
Pregn-4-ene-3,20-dione
T047857-83-0
Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production.
- $38
Size
QTY
CitedEstriol
Oestriol, NSC-12169
T157150-27-1
Estriol (Oestriol) is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA.
- $37
Size
QTY
Select Batch
Purity:99.54%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone utilized alone or combined with estrogens as an oral contraceptive. |
| In vitro | Daily administration of 75 μg of Norgestrel combined with 150 μg of Ethynodiol diacetate and 7.5 μg of Ethinyl estradiol can downregulate plasma concentrations of high-density lipoprotein cholesterol in cynomolgus monkeys. Additionally, a dosage of 6 mg/kg of Ethynodiol diacetate significantly elevates the levels of 3alpha-hydroxy-5alpha-pregnan-20-one and A-homo-3-oxa-5alpha-pregnane-4,20-dione in the urine of female rats, and markedly increases the weight of the rat's pituitary, liver, and kidneys. |
| In vivo | In the presence of an S9 mix, treatment with NDGA inhibits the genotoxic damage induced by Ethynodiol diacetate, which may be attributed to the suppression of cytochrome P450s that prevent the metabolic activation of Ethynodiol diacetate, or due to NDGA's radical scavenging properties. Concurrently, 150 μg/mL Ethynodiol diacetate increases the rate of sister chromatid exchanges and the frequency of chromosomal aberrations in human lymphocytes, and inhibits lymphocyte proliferation. Notably, < 1.5 μM NDGA can reduce the rate of sister chromatid exchanges in human lymphocytes treated with 150 μg/mL Ethynodiol diacetate. |
| Alias | Ethynodiol acetate, 8080 CB |
| Molecular Weight | 384.51 |
| Formula | C24H32O4 |
| Cas No. | 297-76-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (104.03 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Ethynodiol diacetate | purchase Ethynodiol diacetate | Ethynodiol diacetate cost | order Ethynodiol diacetate | Ethynodiol diacetate chemical structure | Ethynodiol diacetate in vivo | Ethynodiol diacetate in vitro | Ethynodiol diacetate formula | Ethynodiol diacetate molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.