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FASN-IN-3

🥰Excellent
Catalog No. T11557Cas No. 2097262-60-5

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

FASN-IN-3

FASN-IN-3

🥰Excellent
Purity: 97.41%
Catalog No. T11557Cas No. 2097262-60-5
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
Pack SizePriceAvailabilityQuantity
1 mg$59In Stock
5 mg$143In Stock
10 mg$230In Stock
25 mg$392In Stock
50 mg$535In Stock
100 mg$762In Stock
200 mg$987In Stock
1 mL x 10 mM (in DMSO)$158In Stock
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Purity:97.41%
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Product Introduction

Bioactivity
Description
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).
In vitro
For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 , results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation.
Chemical Properties
Molecular Weight384.47
FormulaC24H24N4O
Cas No.2097262-60-5
SmilesCc1n[nH]c(c1C)-c1cc(C(=O)N2CC(C2)c2ccc(cc2)C#N)c(C)cc1C
Relative Density.1.26 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 33.33 mg/mL (86.69 mM), Sonication and heating to 80℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6010 mL13.0049 mL26.0098 mL130.0492 mL
5 mM0.5202 mL2.6010 mL5.2020 mL26.0098 mL
10 mM0.2601 mL1.3005 mL2.6010 mL13.0049 mL
20 mM0.1300 mL0.6502 mL1.3005 mL6.5025 mL
50 mM0.0520 mL0.2601 mL0.5202 mL2.6010 mL

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