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IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of respiratory infection.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $54 | In Stock | |
5 mg | $128 | In Stock | |
10 mg | $197 | In Stock | |
25 mg | $277 | In Stock | |
50 mg | $347 | In Stock | |
100 mg | $479 | In Stock | |
1 mL x 10 mM (in DMSO) | $123 | In Stock |
Description | IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of respiratory infection. |
In vitro | IA-alkyne (2.5-10 μM; 1 hour) reacts with cysteines. In-gel fluorescence imaging indicates strong fluorescent intensity of IA-alkyne. Labeled proteome samples are conjugated with a fluorescent rhodamine-azide tag via CuAAC and analyzed by SDS-PAGE. Soluble fractions of HeLa cell lysates (2.0 mg/ml) are treated with IA-alkyne [2]. |
Alias | N-Hex-5-ynyl-2-iodo-acetamide, Iodoacetamide-alkyne |
Molecular Weight | 265.09 |
Formula | C8H12INO |
Cas No. | 930800-38-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/ml (207.48 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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