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IA-Alkyne

Catalog No. T15543Cas No. 930800-38-7
Alias N-Hex-5-ynyl-2-iodo-acetamide, Iodoacetamide-alkyne

IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of respiratory infection.

IA-Alkyne

IA-Alkyne

Catalog No. T15543Alias N-Hex-5-ynyl-2-iodo-acetamide, Iodoacetamide-alkyneCas No. 930800-38-7
IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of respiratory infection.
Pack SizePriceAvailabilityQuantity
1 mg$54In Stock
5 mg$128In Stock
10 mg$197In Stock
25 mg$277In Stock
50 mg$347In Stock
100 mg$479In Stock
1 mL x 10 mM (in DMSO)$123In Stock
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Purity:≥98%
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Product Introduction

Bioactivity
Description
IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of respiratory infection.
In vitro
IA-alkyne (2.5-10 μM; 1 hour) reacts with cysteines. In-gel fluorescence imaging indicates strong fluorescent intensity of IA-alkyne. Labeled proteome samples are conjugated with a fluorescent rhodamine-azide tag via CuAAC and analyzed by SDS-PAGE. Soluble fractions of HeLa cell lysates (2.0 mg/ml) are treated with IA-alkyne [2].
AliasN-Hex-5-ynyl-2-iodo-acetamide, Iodoacetamide-alkyne
Chemical Properties
Molecular Weight265.09
FormulaC8H12INO
Cas No.930800-38-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (207.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7723 mL18.8615 mL37.7230 mL188.6152 mL
5 mM0.7545 mL3.7723 mL7.5446 mL37.7230 mL
10 mM0.3772 mL1.8862 mL3.7723 mL18.8615 mL
20 mM0.1886 mL0.9431 mL1.8862 mL9.4308 mL
50 mM0.0754 mL0.3772 mL0.7545 mL3.7723 mL
100 mM0.0377 mL0.1886 mL0.3772 mL1.8862 mL

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