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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $32 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $228 | In Stock | |
50 mg | $342 | In Stock | |
100 mg | $531 | In Stock | |
1 mL x 10 mM (in DMSO) | $76 | In Stock |
Description | ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. |
Targets&IC50 | GIRK1/2:160nM, GIRK1/4:887nM, GIRK1/3:914 nM |
Alias | ML297 |
Molecular Weight | 328.32 |
Formula | C17H14F2N4O |
Cas No. | 1443246-62-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (137.06 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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