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ML116
Catalog No. T8597Cas No. 744270-00-6
ML116 is a potent and selective STAT3 inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $133 | In Stock | |
| 2 mg | $198 | In Stock | |
| 5 mg | $297 | In Stock | |
| 10 mg | $453 | In Stock | |
| 25 mg | $747 | In Stock | |
| 50 mg | $1,050 | In Stock | |
| 100 mg | $1,420 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $298 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ML116 is a potent and selective STAT3 inhibitor. |
| In vitro | Probe ML116 exhibits a STAT3 IC50 value of approximately 4 micromolar and does not inhibit the STAT1, STAT5, or NFkB signaling pathways (IC50 values greater than 56 micromolar), as determined using cell-based luciferase reporter assays.?Quantitative PCR experiments demonstrated that probe ML116 inhibits transcription of the STAT3-regulated gene BCL3 |
| Molecular Weight | 309.43 |
| Formula | C18H19N3S |
| Cas No. | 744270-00-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | DMSO: 3.1 mg/mL (10 mM)  | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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