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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | In Stock | |
10 mg | $53 | In Stock | |
25 mg | $113 | In Stock | |
50 mg | $193 | In Stock | |
100 mg | $322 | In Stock | |
500 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $33 | In Stock |
Description | MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis. |
In vitro | MPT0B014 (0-1 μM; 48 h) inhibits the growth of A549、H1299 and H226 cell in a dose dependent manner. MPT0B014 (0.05-0.3 μM; 24 and 48 h) arrests cell cycle in G2/M phase and sub-G1 phase in A549 cells, and induces apoptosis[1]. |
In vivo | MPT0B014 (100 mg/kg; i.v./i.p.; daily for 25 days) combined with Erlotinib (25 mg/kg) significantly improved inhibition effect of mouse A549 tumor[1]. |
Molecular Weight | 323.34 |
Formula | C19H17NO4 |
Cas No. | 1215208-59-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 3.23 mg/mL (10 mM) ![]() | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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