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NHE3-IN-1

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Catalog No. T12219Cas No. 632355-68-1

NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).

NHE3-IN-1

NHE3-IN-1

🥰Excellent
Purity: 97.44%
Catalog No. T12219Cas No. 632355-68-1
NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).
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25 mg$51In Stock
50 mg$85In Stock
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Purity:97.44%
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Product Introduction

Bioactivity
Description
NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).
Chemical Properties
Molecular Weight263.75
FormulaC12H10ClN3S
Cas No.632355-68-1
SmilesN(C=1C(C)=CSC1Cl)C=2NC=3C(N2)=CC=CC3
Relative Density.1.474 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (189.57 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7915 mL18.9573 mL37.9147 mL189.5735 mL
5 mM0.7583 mL3.7915 mL7.5829 mL37.9147 mL
10 mM0.3791 mL1.8957 mL3.7915 mL18.9573 mL
20 mM0.1896 mL0.9479 mL1.8957 mL9.4787 mL
50 mM0.0758 mL0.3791 mL0.7583 mL3.7915 mL
100 mM0.0379 mL0.1896 mL0.3791 mL1.8957 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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