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NPX800

🥰Excellent
Catalog No. T9804Cas No. 1693734-80-3
Alias CCT361814

NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.

NPX800

NPX800

🥰Excellent
Purity: 99.26%
Catalog No. T9804Alias CCT361814Cas No. 1693734-80-3
NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$252In Stock
10 mg$395In Stock
25 mg$659In Stock
50 mg$939In Stock
100 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$316In Stock
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Purity:99.26%
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Product Introduction

Bioactivity
Description
NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.
In vitro
NPX800 inhibits cell viability of U20S with IC50 of 56 nM[1].
AliasCCT361814
Chemical Properties
Molecular Weight569.63
FormulaC32H32FN5O4
Cas No.1693734-80-3
SmilesCCN1CCN(Cc2ccc3cc(ccc3n2)C(=O)Nc2cc(NC(=O)c3ccc4OCCOc4c3)ccc2F)CC1
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 95 mg/mL (166.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7555 mL8.7776 mL17.5553 mL87.7763 mL
5 mM0.3511 mL1.7555 mL3.5111 mL17.5553 mL
10 mM0.1756 mL0.8778 mL1.7555 mL8.7776 mL
20 mM0.0878 mL0.4389 mL0.8778 mL4.3888 mL
50 mM0.0351 mL0.1756 mL0.3511 mL1.7555 mL
100 mM0.0176 mL0.0878 mL0.1756 mL0.8778 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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