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Nylestriol

🥰Excellent
Catalog No. T20744Cas No. 39791-20-3
Alias Nilestriolum, LY-49825, LY49825, LY 49825, Lilly 49825

Nylestriol (LY 49825) is an agonist of estrogen receptor.

Nylestriol

Nylestriol

🥰Excellent
Purity: 98.16%
Catalog No. T20744Alias Nilestriolum, LY-49825, LY49825, LY 49825, Lilly 49825Cas No. 39791-20-3
Nylestriol (LY 49825) is an agonist of estrogen receptor.
Pack SizePriceAvailabilityQuantity
5 mg$50In Stock
10 mg$70In Stock
25 mg$114In Stock
50 mg$167In Stock
100 mg$248In Stock
500 mg$535In Stock
1 mL x 10 mM (in DMSO)$66In Stock
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Purity:98.16%
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Product Introduction

Bioactivity
Description
Nylestriol (LY 49825) is an agonist of estrogen receptor.
In vivo
Nylestriol promoted formation of new bone, increase bone density, and improve bone microstructure damage in OVX rats when combining with Simvastatin[1].
AliasNilestriolum, LY-49825, LY49825, LY 49825, Lilly 49825
Chemical Properties
Molecular Weight380.52
FormulaC25H32O3
Cas No.39791-20-3
SmilesC[C@@]12[C@]([C@]3([C@](CC1)(C=4C(CC3)=CC(OC5CCCC5)=CC4)[H])[H])(C[C@@H](O)[C@]2(C#C)O)[H]
Relative Density.1.21 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (65.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6280 mL13.1399 mL26.2798 mL131.3991 mL
5 mM0.5256 mL2.6280 mL5.2560 mL26.2798 mL
10 mM0.2628 mL1.3140 mL2.6280 mL13.1399 mL
20 mM0.1314 mL0.6570 mL1.3140 mL6.5700 mL
50 mM0.0526 mL0.2628 mL0.5256 mL2.6280 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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