Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Primin

🥰Excellent
Catalog No. TN2101Cas No. 15121-94-5

Primin is a natural product stored in trichomes on the leaves and stems of Primula obconica, exhibiting antimycobacterial and strong antineoplastic actions.

Primin

Primin

🥰Excellent
Purity: 98.47%
Catalog No. TN2101Cas No. 15121-94-5
Primin is a natural product stored in trichomes on the leaves and stems of Primula obconica, exhibiting antimycobacterial and strong antineoplastic actions.
Pack SizePriceAvailabilityQuantity
1 mg$59In Stock
5 mg$137In Stock
10 mg$196In Stock
25 mg$335In Stock
50 mg$497In Stock
100 mg$723In Stock
1 mL x 10 mM (in DMSO)$150In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Primin"

Select Batch
Purity:98.47%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Primin is a natural product stored in trichomes on the leaves and stems of Primula obconica, exhibiting antimycobacterial and strong antineoplastic actions.
Targets&IC50
Leishmania donovani:0.711 μM, T. brucei rhodesiense:0.144 μM
In vitro
Primin showed very potent activity against Trypanosoma brucei rhodesiense (IC50 0.144 microM) and Leishmania donovani (IC50 0.711 microM), and revealed low cytotoxicity (IC50 15.4 microM) on mammalian cells. Only moderate inhibitory activity was observed against Mycobacterium tuberculosis, Trypanosoma cruzi, and Plasmodium falciparum. When tested for in vivo efficacy in a Trypanosoma b. brucei rodent model, Primin failed to cure the infection at 20 mg/kg given intraperitoneally. Primin was too toxic in vivo at a higher concentration (30 mg/kg, injected i.p. route) in mice infected with L. donovani.
Chemical Properties
Molecular Weight208.25
FormulaC12H16O3
Cas No.15121-94-5
SmilesC(CCCC)C=1C(=O)C(OC)=CC(=O)C1
Relative Density.1.06 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (288.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8019 mL24.0096 mL48.0192 mL240.0960 mL
5 mM0.9604 mL4.8019 mL9.6038 mL48.0192 mL
10 mM0.4802 mL2.4010 mL4.8019 mL24.0096 mL
20 mM0.2401 mL1.2005 mL2.4010 mL12.0048 mL
50 mM0.0960 mL0.4802 mL0.9604 mL4.8019 mL
100 mM0.0480 mL0.2401 mL0.4802 mL2.4010 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Primin | purchase Primin | Primin cost | order Primin | Primin chemical structure | Primin in vitro | Primin formula | Primin molecular weight