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Puerarin 6''-O-Xyloside

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Purity:98.67%

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COA HNMR HPLC

Puerarin 6''-O-Xyloside

Catalog No. T5S2083Cas No. 114240-18-5

Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2.

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Pack Size	Price	Availability
1 mg	$155	In Stock
5 mg	$197	In Stock
10 mg	$293	In Stock
25 mg	$497	In Stock
50 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$247	In Stock

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Product Introduction

Bioactivity

Description	Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2.
In vivo	The in vivo animal study showed that POS significantly inhibited tumour growth in A549 cells (p?
Animal Research	The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to determine the cytotoxicity of POS (at 10, 20 and 40?μM) in vitro, and xenograft nude mice were established to evaluate the antitumour effect of POS (at 40?mg/kg/d) in vivo by 15 days intraperitoneal injection (ip). To explore its mechanism of action, flow cytometry was performed to determine the pro-apoptotic effect of POS (at 10, 20 and 40?μM). Subsequently, the expression of caspase-3, caspase-7, caspase-9, Bcl-2 and Bax in A549 cells were determined[1].

Chemical Properties

Molecular Weight	548.49
Formula	C26H28O13
Cas No.	114240-18-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 25 mg/mL (45.58 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8232 mL	9.1159 mL	18.2319 mL	91.1594 mL
5 mM	0.3646 mL	1.8232 mL	3.6464 mL	18.2319 mL
10 mM	0.1823 mL	0.9116 mL	1.8232 mL	9.1159 mL
20 mM	0.0912 mL	0.4558 mL	0.9116 mL	4.5580 mL

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