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Radezolid

🥰Excellent
Catalog No. T16718Cas No. 869884-78-6
Alias RX-1741

Radezolid (RX-1741) is a novel oxazolidinone antibiotic.

Radezolid

Radezolid

🥰Excellent
Purity: 97.52%
Catalog No. T16718Alias RX-1741Cas No. 869884-78-6
Radezolid (RX-1741) is a novel oxazolidinone antibiotic.
Pack SizePriceAvailabilityQuantity
1 mg45 €In Stock
5 mg107 €In Stock
10 mg187 €In Stock
25 mg339 €In Stock
50 mg525 €In Stock
100 mg748 €In Stock
1 mL x 10 mM (in DMSO)119 €In Stock
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Purity:97.52%
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Product Introduction

Bioactivity
Description
Radezolid (RX-1741) is a novel oxazolidinone antibiotic.
In vitro
Radezolid consistently demonstrates superior potency to linezolid across all tested bacteria, maintaining this advantage regardless of the bacterium's sensitivity, when the concentration measurements are standardized to weight (mg/L). This is evidenced by Radezolid's MIC values, which are always equal to or lower than those of linezolid—by up to 3 log2 dilutions—for strains susceptible to linezolid, and exhibit an 8-fold potency increase against linezolid-resistant strains. Additionally, Radezolid, alongside TR-700, is effective against mutants with 3-copy alterations at G2447T, G2576T, and G2576T/T2571C positions [1][2].
AliasRX-1741
Chemical Properties
Molecular Weight438.45
FormulaC22H23FN6O3
Cas No.869884-78-6
SmilesCC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 35.07 mg/mL (80 mM), Sonification/heating is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2808 mL11.4038 mL22.8076 mL114.0381 mL
5 mM0.4562 mL2.2808 mL4.5615 mL22.8076 mL
10 mM0.2281 mL1.1404 mL2.2808 mL11.4038 mL
20 mM0.1140 mL0.5702 mL1.1404 mL5.7019 mL
50 mM0.0456 mL0.2281 mL0.4562 mL2.2808 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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