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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
2 mg | $54 | In Stock | |
5 mg | $89 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $197 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $556 | In Stock | |
500 mg | $1,220 | In Stock | |
1 mL x 10 mM (in DMSO) | $107 | In Stock |
Description | Recilisib (ON 01210) is a radioprotectant that activates AKT and PI3K activities in cells. |
In vitro | Recilisib Sodium increases PI3K activity in HFL-1 cells and murine bone marrow cells in response to radiation exposure. Recilisib Sodium treatment in combination with radiation alters the MAPK signaling pathway. |
In vivo | the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice significantly increased by Recilisib Sodium. Recilisib Sodium in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies. Recilisib Sodium treated mice have a progenitor cell population that is never completely depleted by radiation exposure. |
Alias | Ex-RAD, ON 01210 |
Molecular Weight | 336.79 |
Formula | C16H13ClO4S |
Cas No. | 334969-03-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (148.46 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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