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RG7713
🥰Excellent
Catalog No. T4141Cas No. 920022-47-5
Alias RO 5028442
RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.
RG7713
🥰Excellent
Purity: 99.74%
Catalog No. T4141Alias RO 5028442Cas No. 920022-47-5
RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 51 € | In Stock | |
| 5 mg | 114 € | In Stock | |
| 10 mg | 200 € | In Stock | |
| 25 mg | 338 € | In Stock | |
| 50 mg | 506 € | In Stock | |
| 100 mg | 730 € | In Stock |
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Purity:99.74%
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | RG7713 (RO 5028442) has been used in trials studying Autistic Disorder. |
| Targets&IC50 | V1a receptor (human):1 nM(Ki）, V1a receptor (mouse):39nM(Ki） |
| In vitro | RO5028442 (compound 8) has excellent binding in and functional affinity for hV1a, moderate mouse affinity, and excellent selectivity versus human V2 (hV2) and human oxytocin (hOT) receptors. RO5028442 shows high solubility. RO5028442 is found to be highly selective against a panel of 89 targets. Finally, RO5028442 is identified as a suitable compound for clinical studies[1]. |
| Alias | RO 5028442 |
| Molecular Weight | 437.96 |
| Formula | C25H28ClN3O2 |
| Cas No. | 920022-47-5 |
| Smiles | CN(C)CCn1cc(C(=O)N2CCC3(CC2)OCc2ccccc32)c2ccc(Cl)cc12 |
| Relative Density. | 1.28 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.38 mg/mL (10 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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