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RS 100329 hydrochloride
🥰Excellent
Catalog No. T23253Cas No. 1215654-26-4
Alias RS-100329 hcl
RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.
RS 100329 hydrochloride
🥰Excellent
Purity: 100%
Catalog No. T23253Alias RS-100329 hclCas No. 1215654-26-4
RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $106 | In Stock | |
| 25 mg | $232 | In Stock | |
| 50 mg | $345 | In Stock | |
| 100 mg | $493 | In Stock | |
| 500 mg | Inquiry | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor. |
| In vitro | In intact CHO-K1 cells expressing human cloned alpha1A-, alpha1B- and alpha1D-AR showed nanomolar affinity and significant alpha1A-AR subtype selectivity for RS 100329 hydrochloride (pKi 9.6: 126 and 50 fold selectivity) over the alpha1B- and alpha1D-AR subtypes respectively. Noradrenaline-induced contractions of human lower urinary tract (LUT) tissues or rabbit bladder neck were competitively antagonized by RS 100329 hydrochloride (pA2 9.2 and 9.2)[1]. |
| Alias | RS-100329 hcl |
| Molecular Weight | 462.89 |
| Formula | C20H26ClF3N4O3 |
| Cas No. | 1215654-26-4 |
| Smiles | Cl.Cc1c[nH]c(=O)n(CCCN2CCN(CC2)c2ccccc2OCC(F)(F)F)c1=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | H2O: 40 mg/mL (86.4 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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