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Solabegron
🥰Excellent
Catalog No. T12970Cas No. 252920-94-8
Alias GW 427353
Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist that promotes cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR (EC50: 22 nM). It is used to treat overactive bladder and irritable bowel syndrome.
Solabegron
🥰Excellent
Purity: 98.99%
Catalog No. T12970Alias GW 427353Cas No. 252920-94-8
Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist that promotes cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR (EC50: 22 nM). It is used to treat overactive bladder and irritable bowel syndrome.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $53 | In Stock | |
| 5 mg | $167 | In Stock | |
| 10 mg | $273 | In Stock | |
| 25 mg | $497 | In Stock | |
| 50 mg | $672 | In Stock | |
| 100 mg | $893 | In Stock | |
| 200 mg | $1,180 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $178 | In Stock |
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Purity:98.99%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist that promotes cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR (EC50: 22 nM). It is used to treat overactive bladder and irritable bowel syndrome. |
| Targets&IC50 | β3-adrenoceptor:(EC50)22 Nm |
| In vivo | Solabegron(3 mg/kg i.v.)evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. |
| Alias | GW 427353 |
| Molecular Weight | 410.89 |
| Formula | C23H23ClN2O3 |
| Cas No. | 252920-94-8 |
| Smiles | O[C@@H](CNCCNc1cccc(c1)-c1cccc(c1)C(O)=O)c1cccc(Cl)c1 |
| Relative Density. | 1.300 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (608.44 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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