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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $51 | In Stock | |
5 mg | $122 | In Stock | |
10 mg | $222 | In Stock | |
25 mg | $388 | In Stock | |
50 mg | $566 | In Stock | |
100 mg | $790 | In Stock | |
500 mg | $1,620 | In Stock | |
1 mL x 10 mM (in DMSO) | $122 | In Stock |
Description | Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
In vitro | Terevalefim (ANG-3777) (0-10 μM) significantly inhibited cancer cell proliferation in HUVECs[2]. |
In vivo | Terevalefim (ANG-3777) reduces apoptosis, enhances proliferation, and supports organ repair and function in animal models[1]. Additionally, Terevalefim (ANG-3777, 40 mg/kg, IP) induces phosphorylation of the c-Met receptor in rats[2]. |
Molecular Weight | 176.24 |
Formula | C9H8N2S |
Cas No. | 1070881-42-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (567.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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