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Terevalefim
Catalog No. T37596Cas No. 1070881-42-3
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $51 | In Stock | |
| 5 mg | $122 | In Stock | |
| 10 mg | $222 | In Stock | |
| 25 mg | $388 | In Stock | |
| 50 mg | $566 | In Stock | |
| 100 mg | $790 | In Stock | |
| 500 mg | $1,620 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $122 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
| In vitro | Terevalefim (ANG-3777) (0-10 μM) significantly inhibited cancer cell proliferation in HUVECs[2]. |
| In vivo | Terevalefim (ANG-3777) reduces apoptosis, enhances proliferation, and supports organ repair and function in animal models[1]. Additionally, Terevalefim (ANG-3777, 40 mg/kg, IP) induces phosphorylation of the c-Met receptor in rats[2]. |
| Molecular Weight | 176.24 |
| Formula | C9H8N2S |
| Cas No. | 1070881-42-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (567.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
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