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Tracazolate hydrochloride
🥰Excellent
Catalog No. T23470Cas No. 1135210-68-2
Alias Tracazolate (hydrochloride)
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.
Tracazolate hydrochloride
🥰Excellent
Purity: 99.07%
Catalog No. T23470Alias Tracazolate (hydrochloride)Cas No. 1135210-68-2
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $35 | In Stock | |
| 25 mg | Inquiry | In Stock | |
| 50 mg | Inquiry | In Stock |
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Purity:99.07%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and 1.5 μM. |
| In vitro | Tracazolate hydrochloride (10 μM) enhanced the sensitivity of α1β2δ-containing GABAA receptors and increased the maximum current amplitude in oocytes [1]. Tracazolate hydrochloride inhibited α1β1ε, α1β3ε, α1β3, and α6β3γ with EC50s of 4.0 μM, 1.2 μM, 2.7 μM, and 1.1 μM. Tracazolate hydrochloride interacted with γ-aminobutyric acid GABAA receptors, adenosine receptors, and phosphodiesterases [2]. |
| Alias | Tracazolate (hydrochloride) |
| Molecular Weight | 340.85 |
| Formula | C16H25ClN4O2 |
| Cas No. | 1135210-68-2 |
| Smiles | Cl.CCCCNc1c(C(=O)OCC)c(C)nc2n(CC)ncc12 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (293.4 mM), Sonication is recommended. 1eq. HCl: < 34.09 mg/mL | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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