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Tsugaric acid A
🥰Excellent
Catalog No. TN2286Cas No. 174391-64-1
Tsugaric acid A significantly inhibits superoxide anion formation in fMLP/CB-stimulated rat neutrophils and protects human keratinocytes against damage induced by ultraviolet B (UV B) light, indicating that tsugaric acid A can safeguard keratinocytes from photodamage.
Tsugaric acid A
🥰Excellent
Purity: 99.47%
Catalog No. TN2286Cas No. 174391-64-1
Tsugaric acid A significantly inhibits superoxide anion formation in fMLP/CB-stimulated rat neutrophils and protects human keratinocytes against damage induced by ultraviolet B (UV B) light, indicating that tsugaric acid A can safeguard keratinocytes from photodamage.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $64 | In Stock | |
| 5 mg | $153 | In Stock | |
| 10 mg | $247 | In Stock | |
| 25 mg | $418 | In Stock |
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CitedSelect Batch
Purity:99.47%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tsugaric acid A significantly inhibits superoxide anion formation in fMLP/CB-stimulated rat neutrophils and protects human keratinocytes against damage induced by ultraviolet B (UV B) light, indicating that tsugaric acid A can safeguard keratinocytes from photodamage. |
| In vitro | Twelve compounds, including ergosta-7,22-dien-3beta-ol (1), ergosta-7,22-dien-3beta-yl palmitate (2), ergosta-7,22-dien-3-one (3), ergosta-7,22-dien-2beta,3alpha,9alpha-triol (4), 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol (5), ganoderal A (6), ganoderal B (7), ganoderic aldehyde A (8), Tsugaric acid A (9), 3-oxo-5alpha-lanosta-8,24-dien-21-oic acid (10), 3alpha-acetoxy-5alpha-lanosta-8,24-dien-21-oic acid ester beta-d-glucoside (11), and tsugaric acid B (12), were assessed in vitro by determining their inhibitory effects on the chemical mediators released from mast cells, neutrophils, and macrophages. |
| Molecular Weight | 498.74 |
| Formula | C32H50O4 |
| Cas No. | 174391-64-1 |
| Smiles | [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@@H](OC(C)=O)C(C)(C)[C@]1([H])CC3)[C@@H](CCC=C(C)C)C(O)=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.99 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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