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Tubulin inhibitor 8
🥰Excellent
Catalog No. T13226Cas No. 1309925-39-0
Tubulin inhibitor 8 is an inhibitor of tubulin and various cancer cell lines and inhibits tubulin polymerisation and K562 cell growth with an IC50 of 0.73 μM and 14 nM respectively.
Tubulin inhibitor 8
🥰Excellent
Purity: 100%
Catalog No. T13226Cas No. 1309925-39-0
Tubulin inhibitor 8 is an inhibitor of tubulin and various cancer cell lines and inhibits tubulin polymerisation and K562 cell growth with an IC50 of 0.73 μM and 14 nM respectively.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $210 | In Stock | |
| 5 mg | $497 | In Stock | |
| 10 mg | $678 | In Stock | |
| 25 mg | $953 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Tubulin inhibitor 8 is an inhibitor of tubulin and various cancer cell lines and inhibits tubulin polymerisation and K562 cell growth with an IC50 of 0.73 μM and 14 nM respectively. |
| Targets&IC50 | DLD-1 cells:9 nM, Tubulin polymerization:0.73 μM, SK-OV-3 cells:6 nM, BT549 cells:8 nM, NCI-H460 cells:15 nM, K562 cells:14 nM, COLO-205 cells:6 nM, 451Lu cells:2 nM |
| In vitro | Tubulin inhibitor 8 shows excellent antiproliferative potencies with IC50s of 15, 6, 8, 2, 8, 6, and 9 nM for NCIH460, SKOV3, BT549, 451LU, SW480, COLO-205, and DLD-1 tumor cell lines, respectively.[1] |
| Molecular Weight | 342.35 |
| Formula | C21H14N2O3 |
| Cas No. | 1309925-39-0 |
| Smiles | C(=O)(N1C=2C(OC=3C1=CC=CC3)=CC(C#N)=CC2)C4=CC=C(OC)C=C4 |
| Relative Density. | 1.38 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.42 mg/mL (10 mM)  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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