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α-Vitamin E

Catalog No. T1648   CAS 59-02-9
Synonyms: Dexrabeprazole Sodium, Vitamin E, Alpha-Tocopherol, D-α-Tocopherol, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol

α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.

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α-Vitamin E Chemical Structure
α-Vitamin E, CAS 59-02-9
Pack Size Availability Price/USD Quantity
50 mg In stock $ 38.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 99.89%
Purity: 98.76%
Purity: 98.5%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
In vitro vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1].
In vivo Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1].
Cell Research For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference)
Synonyms Dexrabeprazole Sodium, Vitamin E, Alpha-Tocopherol, D-α-Tocopherol, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol
Molecular Weight 430.71
Formula C29H50O2
CAS No. 59-02-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12 mg/mL (27.86 mM)

TargetMolReferences and Literature

1. Kang TH, et al. PLoS One. 2014, 9(7):e103562. 2. Wang S, Li F, Qiao R, et al. Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics[J]. ACS nano. 2018 Dec 26;12(12):12380-12392.

TargetMolCitations

1. Wang S, Li F, Qiao R, et al. Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics. ACS nano. 2018 Dec 26;12(12):12380-12392. 2. He F, Huang X, Wei G, et al. Regulation of ACSL4-Catalyzed Lipid Peroxidation Process Resists Cisplatin Ototoxicity. Oxidative Medicine and Cellular Longevity. 2022 3. Zhang H, Liang B, Sang X, et al.Discovery of Potential Inhibitors of SARS-CoV-2 Main Protease by a Transfer Learning Method.Viruses.2023, 15(4): 891.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Marine Natural Product Library Miao medicine Compound Library Tobacco Monomer Library Anti-Cancer Drug Library Anti-Tumor Natural Product Library Anti-Breast Cancer Compound Library Anti-COVID-19 Compound Library Immunology/Inflammation Compound Library Traditional Chinese Medicine Monomer Library

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Keywords

α-Vitamin E 59-02-9 Apoptosis Chromatin/Epigenetic Cytoskeletal Signaling Immunology/Inflammation Metabolism Microbiology/Virology NF-Κb Others oxidation-reduction Antibacterial Endogenous Metabolite PKC GST Reactive Oxygen Species Influenza Virus Ferroptosis peroxyl Dexrabeprazole Sodium Antioxidant radical Vitamin E D-a-Tocopherol D-alpha-Tocopherol αVitamin E Alpha-Tocopherol D-α-Tocopherol 5,7,8-Trimethyltocol inhibit α Vitamin E α-Tocopherol alpha-Vitamin E Bacterial Inhibitor scavenger a-Tocopherol a-Vitamin E (+)-alpha-Tocopherol inhibitor

 

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