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(±)-Anatoxin A hydrochloride
🥰Excellent
Catalog No. T22478LCas No. 70470-07-4
Alias (±)-ATX-a hydrochloride, (±)-Anatoxin A hydrochloride (1219922-30-1 Free base)
(±)-Anatoxin A hydrochloride is the salt form of (±)-Anatoxin A.(±)-Anatoxin A is a potent neurotoxic naturally occurring alkaloid known as a rapid death factor (VFDF), a potent, direct, and selective agonist of the nAchR (nicotinic acetylcholine receptor), also known as the nicotinic receptor agonist.
(±)-Anatoxin A hydrochloride
🥰Excellent
Purity: 98.31%
Catalog No. T22478LAlias (±)-ATX-a hydrochloride, (±)-Anatoxin A hydrochloride (1219922-30-1 Free base)Cas No. 70470-07-4
(±)-Anatoxin A hydrochloride is the salt form of (±)-Anatoxin A.(±)-Anatoxin A is a potent neurotoxic naturally occurring alkaloid known as a rapid death factor (VFDF), a potent, direct, and selective agonist of the nAchR (nicotinic acetylcholine receptor), also known as the nicotinic receptor agonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock |
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CitedSelect Batch
Purity:98.31%
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Product Introduction
Bioactivity
Chemical Properties
| Description | (±)-Anatoxin A hydrochloride is the salt form of (±)-Anatoxin A.(±)-Anatoxin A is a potent neurotoxic naturally occurring alkaloid known as a rapid death factor (VFDF), a potent, direct, and selective agonist of the nAchR (nicotinic acetylcholine receptor), also known as the nicotinic receptor agonist. |
| In vitro | ACT-451840 has a 50% inhibitory concentration of 0.4 nM against the drug-susceptible P. falciparum NF54 strain; ACT-451840 effectively blocks male gamete formation from the gametocyte stage at a 50% inhibitory concentration of 5.89 nM, and blocks mosquito oocyst development in a dose-dependent manner at a 50% inhibitory concentration of 30 nM. [2] |
| In vivo | In the in vivo efficacy model, the 90% effective dose against P. falciparum of ACT-451840 was 3.7 mg/kg and the 90% effective dose against P. berghei was 13 mg/kg. |
| Alias | (±)-ATX-a hydrochloride, (±)-Anatoxin A hydrochloride (1219922-30-1 Free base) |
| Molecular Weight | 201.69 |
| Formula | C10H16ClNO |
| Cas No. | 70470-07-4 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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