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1-Hydroxyanthraquinone

🥰Excellent
Catalog No. T37101Cas No. 129-43-1

1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.

1-Hydroxyanthraquinone

1-Hydroxyanthraquinone

🥰Excellent
Purity: 98.83%
Catalog No. T37101Cas No. 129-43-1
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
Pack SizePriceAvailabilityQuantity
1 g$29In Stock
5 g$68In Stock
10 g$98In Stock
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Purity:98.83%
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Product Introduction

Bioactivity
Description
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
In vitro
1-Hydroxyanthraquinone (5 and 500 μM) increases the percentage of isolated rat hepatocytes undergoing unscheduled DNA synthesis, indicating genotoxic activity[2].
In vivo
Dietary administration of 1-Hydroxyanthraquinone (1%) induces formation of cecum and colon adenocarcinomas, as well as hepatocellular carcinomas, in rats[2].
Chemical Properties
Molecular Weight224.21
FormulaC14H8O3
Cas No.129-43-1
SmilesOC1=CC=CC2=C1C(=O)C1=C(C=CC=C1)C2=O
Relative Density.1.423g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Chloroform: 30 mg/mL
DMSO: 1 mg/mL, Sonication is recommended.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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