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1-Hydroxyanthraquinone
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
Catalog No. T37101Cas No. 129-43-1
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Purity:98.83%
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1-Hydroxyanthraquinone
Catalog No. T37101Cas No. 129-43-1
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 g | $29 | In Stock | |
| 5 g | $68 | In Stock | |
| 10 g | $98 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | 1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response. |
| In vitro | 1-Hydroxyanthraquinone (5 and 500 μM) increases the percentage of isolated rat hepatocytes undergoing unscheduled DNA synthesis, indicating genotoxic activity[2]. |
| In vivo | Dietary administration of 1-Hydroxyanthraquinone (1%) induces formation of cecum and colon adenocarcinomas, as well as hepatocellular carcinomas, in rats[2]. |
| Molecular Weight | 224.21 |
| Formula | C14H8O3 |
| Cas No. | 129-43-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Chloroform: 30 mg/mL DMSO: 1 mg/mL, Sonication is recommended.  |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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