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5-Methyltryptamine hydrochloride
🥰Excellent
Catalog No. T19813Cas No. 1010-95-3
Alias α-helical CRF 9-41 acetate(90880-23-2 Free base), 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride
5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.
5-Methyltryptamine hydrochloride
🥰Excellent
Purity: 98%
Catalog No. T19813Alias α-helical CRF 9-41 acetate(90880-23-2 Free base), 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochlorideCas No. 1010-95-3
5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $29 | In Stock | |
| 10 mg | $42 | In Stock | |
| 25 mg | $68 | In Stock | |
| 50 mg | $98 | In Stock | |
| 100 mg | $145 | In Stock | |
| 200 mg | $213 | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | 5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock. |
| In vitro | 5-Methyltryptamine stimulates breakdown of endogenous [3H]inositol-labeled phosphoinositides in membranes prepared from blowfly salivary gland homogenates. 5-Methyltryptamine, in the presence of 10 microM GTP gamma S, increased the rate of inositol trisphosphate formation by approximately 500% within 30 s[1]. |
| In vivo | 5-Methyltryptamine contracts trachea with lower potency (-log EC50 < 5) than 5-HT (-log EC50 = 6.98). Guinea pig tracheal contraction to 5-HT and 5-Methyltryptamine is inhibited by 1-(1-naphthyl)piperazine (1-NP, 30 nM)[2]. |
| Alias | α-helical CRF 9-41 acetate(90880-23-2 Free base), 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride |
| Molecular Weight | 210.703 |
| Formula | C11H15ClN2 |
| Cas No. | 1010-95-3 |
| Smiles | Cl.CC1=CC=C2NC=C(CCN)C2=C1 |
| Relative Density. | 1.126g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Soluble |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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