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9-CP-Ade Mesylate

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Purity:99.91%

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COA HNMR HPLC LCMS

9-CP-Ade Mesylate

Catalog No. T23588Cas No. 189639-09-6

9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.

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Pack Size	Price	Availability
1 mg	$61	In Stock
5 mg	$147	In Stock
10 mg	$228	In Stock
25 mg	$419	In Stock
50 mg	$619	In Stock

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Product Introduction

Bioactivity

Description	9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.
In vitro	9-CP-Ade Mesylate (200 μM; 30 min) inhibits cAMP response element binding protein (CREB) activation and completely blocks neurogenesis in PC12 cells.[1] 9-CP-Ade Mesylate (100 μM; 30 min) attenuates the effects of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization, thereby participating in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice.[2] 9-CP-Ade Mesylate (100 μM; 6 h) promotes restoration of the keratinocyte permeability barrier by inhibiting cAMP synthesis in male hairless mice.[3]
Alias	9-Cyclopentyladenine monomethanesulfonate, 9 CP Ade Mesylate, 9CPAde Mesylate

Chemical Properties

Molecular Weight	299.35
Formula	C11H17N5O3S
Cas No.	189639-09-6

Storage & Solubility Information

Storage

|Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 29.94 mg/mL (100 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3406 mL	16.7029 mL	33.4057 mL	167.0286 mL
5 mM	0.6681 mL	3.3406 mL	6.6811 mL	33.4057 mL
10 mM	0.3341 mL	1.6703 mL	3.3406 mL	16.7029 mL
20 mM	0.1670 mL	0.8351 mL	1.6703 mL	8.3514 mL
50 mM	0.0668 mL	0.3341 mL	0.6681 mL	3.3406 mL
100 mM	0.0334 mL	0.1670 mL	0.3341 mL	1.6703 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc