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9-FLUORENOL

9-FLUORENOL
9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.
Catalog No. T8633Cas No. 1689-64-1
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Purity:99.98%
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9-FLUORENOL

Catalog No. T8633Cas No. 1689-64-1

9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.
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Product Introduction

Bioactivity
Description
9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 µM, and a major metabolite of a compound developed as a wakefulness-promoting agent.
In vivo
Fluorenol(100 mg/kg) is reported to promote wakefulness in mice with 39% increased effectiveness over the structurally related compound, modafinil[1]
Chemical Properties
Molecular Weight182.22
FormulaC13H10O
Cas No.1689-64-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (137.2 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.4879 mL27.4394 mL54.8787 mL274.3936 mL
5 mM1.0976 mL5.4879 mL10.9757 mL54.8787 mL
10 mM0.5488 mL2.7439 mL5.4879 mL27.4394 mL
20 mM0.2744 mL1.3720 mL2.7439 mL13.7197 mL
50 mM0.1098 mL0.5488 mL1.0976 mL5.4879 mL
100 mM0.0549 mL0.2744 mL0.5488 mL2.7439 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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