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AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $29 | In Stock | |
5 mg | $49 | In Stock | |
10 mg | $89 | In Stock | |
25 mg | $152 | In Stock | |
50 mg | $226 | In Stock | |
100 mg | $335 | In Stock | |
200 mg | $479 | In Stock |
Description | AC-55541 (AOB2796) is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. |
Targets&IC50 | PAR2:200-1000 nM(EC50) |
Kinase Assay | Inhibition Kinetics Studies: Recombinant human wild-type and T790M/L858R double mutant EGFR, both Nterminal GST-tagged, are used in the assay. The Omnia continuous read assay is performed as described by the vendor. |
Alias | AOB2796 |
Molecular Weight | 518.36 |
Formula | C25H20BrN5O3 |
Cas No. | 916170-19-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 5.18 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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