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AG1557

AG1557
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Catalog No. T2034Cas No. 189290-58-2
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Purity:99.23%
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AG1557

Purity: 99.23%
Catalog No. T2034Alias AG-1557, AG 1557Cas No. 189290-58-2

AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$41In Stock
25 mg$76In Stock
50 mg$123In Stock
100 mg$197In Stock
200 mg$295In Stock
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Product Introduction

Bioactivity
Description
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Targets&IC50
EGFR:8.194 (pIC50)
AliasAG-1557, AG 1557
Chemical Properties
Molecular Weight407.21
FormulaC16H14IN3O2
Cas No.189290-58-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.07 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4557 mL12.2787 mL24.5574 mL122.7868 mL
5 mM0.4911 mL2.4557 mL4.9115 mL24.5574 mL
10 mM0.2456 mL1.2279 mL2.4557 mL12.2787 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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