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AG957

Catalog No. T21785 CAS 140674-76-6

Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors[1].

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AG957, CAS 140674-76-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 188.00
5 mg	In stock	$ 342.00
10 mg	In stock	$ 558.00
25 mg	In stock	$ 898.00
50 mg	In stock	$ 1,230.00
100 mg	In stock	$ 1,660.00
1 mL * 10 mM (in DMSO)	In stock	$ 353.00

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Purity: 99.27%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	273.28
Formula	C15H15NO4
CAS No.	140674-76-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (219.56 mM)

References and Literature

1. Bhatia R, Munthe HA, Verfaillie CM. Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors. Leukemia. 1998 Nov;12(11):1708-17.

Related compound libraries

This product is contained In the following compound libraries：

Tyrosine Kinase Inhibitor Library Inhibitor Library Anti-Cancer Metabolism Compound Library Kinase Inhibitor Library Hematonosis Compound Library Cytoskeletal Signaling Pathway Compound Library Bioactive Compound Library Angiogenesis related Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library

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AT9283 Pivanex PPY A Gypsogenin BCR-ABL-IN-8 ZM 306416 Vodobatinib CpCDPK1/TgCDPK1-IN-1

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AG957 140674-76-6 Angiogenesis Cytoskeletal Signaling Tyrosine Kinase/Adaptors Bcr-Abl paxillin NSC654705 c-Abl lipopolysaccharide AG 957 Tyrphostin AG-957 integrins leukemia tyrosine Tyrphostin AG 957 hematopoiesis NSC-654705 NSC 654705 AG-957 Tyrphostin AG957 kinase BCR/ABL inhibit cytoskeleton Inhibitor Chronic myelogenous inhibitor

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