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Acelarin

Catalog No. T4060Cas No. 840506-29-8
Alias NUC-1031

Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.

Acelarin

Acelarin

Purity: 98.56%
Catalog No. T4060Alias NUC-1031Cas No. 840506-29-8
Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Pack SizePriceAvailabilityQuantity
1 mg$38In Stock
2 mg$54In Stock
5 mg$89In Stock
10 mg$147In Stock
25 mg$288In Stock
50 mg$513In Stock
100 mg$746In Stock
1 mL x 10 mM (in DMSO)$98In Stock
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Purity:98.56%
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Product Introduction

Bioactivity
Description
Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Targets&IC50
DNA synthesis:EC50 : 0.2 nM
AliasNUC-1031
Chemical Properties
Molecular Weight580.47
FormulaC25H27F2N4O8P
Cas No.840506-29-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (94.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7227 mL8.6137 mL17.2274 mL86.1371 mL
5 mM0.3445 mL1.7227 mL3.4455 mL17.2274 mL
10 mM0.1723 mL0.8614 mL1.7227 mL8.6137 mL
20 mM0.0861 mL0.4307 mL0.8614 mL4.3069 mL
50 mM0.0345 mL0.1723 mL0.3445 mL1.7227 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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