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Acelarin

Acelarin
Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Catalog No. T4060Cas No. 840506-29-8
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Purity:98.56%
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Acelarin

Purity: 98.56%
Catalog No. T4060Alias NUC-1031Cas No. 840506-29-8

Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
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Pack SizePriceAvailabilityQuantity
1 mg$38In Stock
2 mg$54In Stock
5 mg$89In Stock
10 mg$147In Stock
25 mg$288In Stock
50 mg$513In Stock
100 mg$746In Stock
1 mL x 10 mM (in DMSO)$98In Stock
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Product Introduction

Bioactivity
Description
Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Targets&IC50
DNA synthesis:EC50 : 0.2 nM
AliasNUC-1031
Chemical Properties
Molecular Weight580.47
FormulaC25H27F2N4O8P
Cas No.840506-29-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (94.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7227 mL8.6137 mL17.2274 mL86.1371 mL
5 mM0.3445 mL1.7227 mL3.4455 mL17.2274 mL
10 mM0.1723 mL0.8614 mL1.7227 mL8.6137 mL
20 mM0.0861 mL0.4307 mL0.8614 mL4.3069 mL
50 mM0.0345 mL0.1723 mL0.3445 mL1.7227 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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