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Ampicillin Trihydrate

Catalog No. T0814 CAS 7177-48-2

Synonyms: NCI-C56086

Ampicillin Trihydrate (NCI-C56086), a broad-spectrum semisynthetic derivative of aminopenicillin, is a β-lactam antibiotic.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Ampicillin Trihydrate Chemical Structure

Ampicillin Trihydrate, CAS 7177-48-2

Pack Size	Availability	Price/USD
500 mg	In stock	$ 42.00
1 g	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.95%

Purity: 99.53%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ampicillin Trihydrate (NCI-C56086), a broad-spectrum semisynthetic derivative of aminopenicillin, is a β-lactam antibiotic.
In vitro	In sheep and goats, the half-life of Ampicillin Trihydrate (10 mg/kg) is 2.48 and 1.2 hours, respectively. In mice and rats, doses of Ampicillin Trihydrate ranging from (0.18 kg/kg to 3 kg/kg) do not induce diarrhea or cause mortality.
In vivo	When added to SP34, Ampicillin Trihydrate (500 mg) exhibits effective bactericidal activity and inhibits growth.

Synonyms	NCI-C56086
Molecular Weight	403.45
Formula	C16H19N3O4S·3H2O
CAS No.	7177-48-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4.03 mg/mL (10 mM), Sonification is recommended

References and Literature

1. Lacy MK, et al. Antimicrob Agents Chemother, 1999, 43(3), 672-677. 2. Elsheikh HA, et al. J Vet Pharmacol Ther, 1997, 20(4), 262-266. 3. Dunnick JK, et al. Toxicology, 1989, 56(2), 123-136. 4. Membrez M, et al. FASEB J, 2008, 22(7), 2416-2426. 5. Brown MP, et al. Equine Vet J, 1984, 16(4), 371-373.

Citations

1. Li T, Lu D, Yao C, et al. Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice. Nature Communications. 2022, 13(1): 1-16.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Microbial Natural Product Library Covalent Inhibitor Library Anti-infective Natural Product Library Antibiotics Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library Covalent Natural Product Library Bioactive Compound Library Anti-Bacterial Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ampicillin Trihydrate 7177-48-2 Microbiology/Virology Antibiotic Antibacterial NCI-C56086 NCI-C-56086 Bacterial inhibit NCI-C 56086 Ampicillin Inhibitor inhibitor

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