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BAY 41-8543

Catalog No. T21712 CAS 256498-66-5

BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).

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BAY 41-8543, CAS 256498-66-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
In vivo	BAY 41-8543 has similar vasodilator activity in the pulmonary and systemic vascular beds in the rat[1].

Molecular Weight	420.452
Formula	C21H21FN8O
CAS No.	256498-66-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: insoluble or slightly soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Badejo A M , Nossaman V E , Pankey E A , et al. Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase stimulator, BAY 41-8543, are modulated by nitric oxide.[J]. American Journal of Physiology: Heart & Circulatory Physiology, 2010, 68(4):H1153-H16159.

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Keywords

BAY 41-8543 256498-66-5 G蛋白偶联受体其他 Guanylate cyclase Others BAY 418543 vascular systemic antiplatelet vasodilator soluble pulmonary orally nitric beds cardiovascular BAY 41 8543 Guanylate Cyclase Inhibitor sGC oxide inhibit inhibitor

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