144
17
15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7713 | Benzyl nicotinate | Rubriment,Pycaril | GPR |
Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor | |||
T11353 | Gallopamil | Methoxyverapamil | Calcium Channel |
Gallopamil (Methoxyverapamil) inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy der... | |||
T1132 | Nicergoline | Nicergolinum,Nimergoline | Adrenergic Receptor |
Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins. | |||
T21607 | Ataciguat | HMR-1766 | Others , Guanylate cyclase |
Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator. | |||
T11353L | Gallopamil hydrochloride | Methoxyverapamil hydrochloride | Calcium Channel |
Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies. | |||
T21712 | BAY 41-8543 | Others , Guanylate cyclase | |
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). | |||
T22459 | Xanthinol Nicotinate | Angioamin,Complamin | Others |
Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy. | |||
T22830 | GYY4137 | GYY 4137 morpholine salt | Others |
GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity. | |||
T0957 | Isradipine | PN 200-110 | Calcium Channel , Autophagy |
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc... | |||
T8135 | Minoxidil sulfate | Minoxidil sulphate,U-58838 | Potassium Channel |
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil. | |||
T0368 | Cinepazide maleate | MD-67350,Vasodistal,Brendil | Calcium Channel |
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator. | |||
T1056 | Isoprenaline hydrochloride | NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl | PI3K , Endogenous Metabolite , Adrenergic Receptor , PDE |
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties. | |||
T0154 | Nebivolol hydrochloride | R 065824 hydrochloride,Nebivolol HCl,R-65824 | Apoptosis , Adrenergic Receptor |
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us... | |||
T1606 | Fasudil | HA-1077,AT877 | ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy |
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | |||
T9537 | N'-Nitro-D-arginine | N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid | Others |
N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block. | |||
T3060 | Fasudil hydrochloride | Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 | ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy |
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | |||
T15757 | Limaprost | 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206 | PGE Synthase |
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood... | |||
T31805 | Flosequinan | Others | |
Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure. | |||
T12315 | OR-1896 | PDE | |
OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator. | |||
T30615 | Bupicomide | ||
Bupicomide is a vasodilator that significantly reduces systolic, diastolic, and means arterial pressure, as well as peripheral vascular resistance. | |||
T0080 | Trapidil | Rocornal,Trapymine,Avantrin,Trapymin,AR-12008 | PDGFR , PDE |
Trapidil (Avantrin) is a coronary vasodilator agent. It was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease. | |||
T0151 | Efloxate | Angorlisin | Adrenergic Receptor |
Efloxate (Angorlisin), a vasodilator, is utilized in the treatment of chronic coronary insufficiency. | |||
T26939 | Cadralazine | ISF 2469,ISF-2469,ISF2469 | Others |
Cadralazine (ISF 2469) is a peripheral arteriolar vasodilator and can be used in studies about acting as an antihypertensive drug. | |||
T33589 | Nanterinone | UK-61260,UK61260,UK 61260 | PDE |
Nanterinone (UK 61260), an orally available partial phosphodiesterase inhibitor, is a novel positive inotropic and balanced vasodilator compound.Nanterinone, when administered orally, results in significant improvements ... | |||
T1479 | Isosorbide dinitrate | Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate | Others , NO Synthase |
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris. | |||
T0003 | Sodium Nitroprusside | Sodium Nitroferricyanide,Nitroprusside Sodium,Ro 21-2498 | Others |
Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously. | |||
T20444 | Hexyl nicotinate | AI3 15769,AI3-15769,AI315769 | Others |
Hexyl nicotinate (AI3 15769) is a cutaneous vasodilator and can be used in research on non-immunologic contact urticaria on the scalp, face, and back. | |||
T33272 | Mefenidil | McN-2378,McN 2378 | Others |
Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model. | |||
T68036 | Carprazidil | Others | |
Carprazidil is a potent vasodilator used to treat severe hypertension and mild heart failure. | |||
T0163 | Nisoldipine | BAY-k 5552 | Calcium Channel , Reactive Oxygen Species |
Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. | |||
T0317 | Buflomedil hydrochloride | Buflomedil HCl,Fonzylane,Loftyl | Adrenergic Receptor |
Buflomedil hydrochloride (Fonzylane), a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease. | |||
T21478 | Cromakalim | BRL-34915,BRL 34915,(±)-Cromakalim,BRL34915 | |
Cromakalim, a potassium channel-opening vasodilator, acts on ATP-sensitive potassium channels and so causes membrane hyperpolarization, it can be used to treat hypertension as it will relax vascular smooth muscle to lowe... | |||
T6863 | Isosorbide Mononitrate | Isosorbide-5-mononitrate,Imdur,Mononit,Corangin,Monoket,Elantan | Others , Autophagy |
Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure. | |||
TP2233L | CGRP (rat) acetate | Others | |
CGRP (rat) acetate is a calcitonin gene-related peptide (CGRP). CGRP (rat) acetate is a potent vasodilator. | |||
T24579 | Oxyfedrine L-form HCl | Modacor,Oxyfedrine L-form hydrochloride,D563,Ildamen,D 563,D-563 | Adrenergic Receptor |
Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent. | |||
T0246 | Betahistine dihydrochloride | PT-9,Betahistine 2HCl | Histamine Receptor |
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. | |||
T10502 | Benzcyclane | Benzcyclan,Bencyclane | Others , Platelet aggregation |
Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders. | |||
T24786 | SG-209 | ||
SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator. | |||
T1299 | 3-Pyridinemethanol | Nicotinyl alcohol,Roniacol | Others |
3-Pyridinemethanol (Roniacol) is an alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened GANGRENE. | |||
T6991 | Nitroprusside disodium dihydrate | Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate | Guanylate cyclase , Autophagy |
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood. | |||
TNU1119 | N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite | Nucleoside Antimetabolite/Analog | |
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer research. | |||
T0451 | Minoxidil | U10858 | Potassium Channel , COX |
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects. | |||
T0712 | Suloctidil | ATPase , Platelet aggregation | |
Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. | |||
T0126 | Diazoxide | SRG-95213,Sch-6783,Proglycem | ATPase , Potassium Channel , Autophagy |
Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group. | |||
TNU0266 | 9-(β-D-Xylofuranosyl)adenine | Xylosyladenine,Adenine xyloside | Nucleoside Antimetabolite/Analog |
9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has anticancer activity. | |||
T21447 | Tolazoline | Priscol,Priscoline,Pridazole,Divascol,Vasimid,Benzalolin | Adrenergic Receptor |
Tolazoline (Benzalolin), a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels. It has also been used successfully as an antidote to reverse th... | |||
TP2044L | α-CGRP (human) acetate | α-CGRP (human) acetate (90954-53-3 free base) | Others |
α-CGRP (human) acetate is a regulatory neuropeptide of 37 amino acids. It is the most potent vasodilator known to date and has inotropic and chronotropic effects. | |||
T0246L | Betahistine mesylate | Extovyl,Melopat,Meginalisk | Histamine Receptor |
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. | |||
T1265 | Amrinone | Inamrinone,Inocor,Wincoram | TNF , PDE |
Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity. | |||
T13804 | OPC-28326 | Adrenergic Receptor | |
OPC-28326 is a specific an α2-adrenergic receptor antagonist and acts as a peripheral vasodilator. OPC-28326 inhibits α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8198 | Visnagin | Others | |
Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. | |||
T1186 | Ifenprodil Tartrate | Potassium Channel , NMDAR , iGluR | |
Ifenprodil is a selective NMDA receptor (glutamate) antagonist. | |||
T9257 | 1,3-BUTANEDIOL | Others , Endogenous Metabolite | |
1,3-Butanediol (BD) is a ketogenic substance. Ketone bodies are essential energy substrates in the absence of exogenous nutrients, and more recently, they have been suggested to prevent disease and improve longevity. | |||
T1626 | Prostaglandin E1 | PGE1,Alprostadil | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in... | |||
T2149 | Vinburnine | Eburnalritardo,L-Eburnamonine,Vincamone,(-)-Eburnamonine,(-)-Vincamone | Others , Drug Metabolite |
Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine. | |||
T13302 | Viquidil hydrochloride | Quinotoxine hydrochloride | Others |
Viquidil hydrochloride (Quinotoxine hydrochloride) is an isomer of Quinidine. Viquidil hydrochloride is an agent of cerebral vasodilator with antithrombotic activity. | |||
T1431 | Khellin | Amicardine,Methafrone,Visammin | EGFR , Others |
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action. | |||
T0625 | Theobromine | 3, 7-Dimethylxanthine,3,7-Dimethylxanthine | Endogenous Metabolite , PDE , Adenosine Receptor |
Theobromine (3,7-Dimethylxanthine), a xanthine alkaloid, is used as a bronchodilator and as a vasodilator. | |||
T5940 | Proxyphylline | 7-(2-Hydroxypropyl)theophylline | PDE , Adenosine Receptor |
Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator. | |||
T0583 | Meso-Erythritol | Erythrit,Erythritol,Phycitol | Endogenous Metabolite |
meso-Erythritol (Phycitol) is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. | |||
T0965 | Histamine | Ergamine | 5-HT Receptor , Endogenous Metabolite , Histamine Receptor |
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... | |||
T6534 | Histamine dihydrochloride | peremin,Ceplene,Histamine 2HCl | Endogenous Metabolite , Histamine Receptor |
Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodila... | |||
T1286 | Vincamine | Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval | GPR , Others |
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. | |||
T0892 | Diphylline | Dyphylline,Diprophylline | PDE , Adenosine Receptor |
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies... | |||
T4S1551 | Cinnamaldehyde | Cinnamic Aldehyde | HIF |
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express... | |||
TN1246 | 3-Deoxysappanone B | Others | |
3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings. | |||
TN2534 | 1-Hydroxy-2,3,5-trimethoxyxanthone | IκB/IKK , Calcium Channel , NOS , 5-HT Receptor , COX | |
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type vo... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00383 | ACE2/ACEH Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPY-02432 | VEGF164 Protein, Rat, Recombinant | Rat | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-01717 | VEGF164 Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-03698 | VEGF121b Protein, Human, Recombinant | Human | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-04911 | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPK-00551 | ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi) | Cynomolgus | HEK293 |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPK-00382 | ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPK-00552 | ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated | Cynomolgus | HEK293 |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPY-01656 | VEGF183 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-05798 | VEGF145 Protein, Human, Recombinant | Human | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-03705 | VEGF164 Protein, Canine, Recombinant | Canine | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-03080 | VEGF165 Protein, Danio rerio (zebrafish), Recombinant | Danio rerio (zebrafish) | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-00410 | EPHX2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the ... | |||
TMPH-03081 | ACE2 Protein, Paguma larvata, Recombinant (hFc) | Paguma larvata | HEK293 |
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin ... | |||
TMPJ-01166 | IGFBP-7 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ... |